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About Us

Eccogene is a clinical stage biopharmaceutical company developing best-in-class small molecule therapeutics for cardiometabolic and inflammatory conditions. Since its founding, the Company has been dedicated to discovering safer and more effective oral therapies that can be used alone or synergistically with a GLP-1 receptor agonist to treat conditions beyond weight management.

Eccogene's diverse pipeline of oral small molecule candidates leverages the Company's world-class expertise in translational research, small molecule discovery, and deep understanding of diabetes, weight management and cardiometabolic disease pathways. Our oral small molecule GLP-1 receptor agonist, ECC5004, is a potentially best-in-class asset, which we licensed to AstraZeneca. Eccogene also has clinical programs underway that target THR-β and SSAO, as well as preclinical programs targeting proven pathways, such as amylin and GIP. The Company's complementary pipeline fulfills its mission to improve care and expand access to cost effective medicines for millions of patients worldwide who suffer from cardiometabolic and inflammatory diseases.

Eccogene utilizes its deep translational research expertise, particularly in small molecule design and disease state, to develop better therapeutics. Our assets are designed to have best-in-class properties, including better efficacy, oral, once-daily dosing, as well as improved PK/PD and safety profiles that make them well-suited for combination use to improve clinical benefit.

Pipeline

IndicationInd.
PreclinicalPreclin.
Phase 1/1bPh. 1/1b
Phase 2/2bPh. 2/2b
Phase 3Ph. 3
PartnerPart.
Clinical Programs
ECC5004 SM GLP-1RA
ECC5004 SM GLP-1RA
T2D
T2D
AstraZeneca logo
Weight Management
Weight Management
AstraZeneca logo
Weight Management / T2D{sup}(2){/sup}
Weight Management / T2D{sup}(2){/sup}
ECC4703 THR-β Agonist
ECC4703 THR-β Agonist
MASH
MASH
Weight Management
Weight Management
ECC0509 SSAO Inhibitor
ECC0509 SSAO Inhibitor
OA Pain
OA Pain
MASH
MASH
Preclinical Programs
GIP Program SM GIPR
GIP Program SM GIPR
Metabolic Diseases
Metabolic Diseases
Amylin Program SM AmylinR
Amylin Program SM AmylinR
Metabolic Diseases
Metabolic Diseases
(1) AstraZeneca led trials
(2) China trial

Contact Us

United States

255 Main Street, Suite 1002
Cambridge, MA 02142

General:
Media:
Investors:

China

Rm. 402A, No. 326, AiDiSheng Road
Zhangjiang, Pudong New District
Shanghai, 201203