Unlocking the full potential of GLP-1-based therapy
Advancing small molecules
that target obesity and its
associated comorbidities
About Us
Eccogene is a clinical stage biopharmaceutical company developing best-in-class small molecule therapeutics for cardiometabolic and inflammatory conditions. Since its founding, the Company has been dedicated to discovering safer and more effective oral therapies that can be used alone or synergistically with a GLP-1 receptor agonist to treat conditions beyond weight management.
Eccogene's diverse pipeline of oral small molecule candidates leverages the Company's world-class expertise in translational research, small molecule discovery, and deep understanding of diabetes, weight management and cardiometabolic disease pathways. Our oral small molecule GLP-1 receptor agonist, ECC5004, is a potentially best-in-class asset, which we licensed to AstraZeneca. Eccogene also has clinical programs underway that target THR-β and SSAO, as well as preclinical programs targeting proven pathways, such as amylin and GIP. The Company's complementary pipeline fulfills its mission to improve care and expand access to cost effective medicines for millions of patients worldwide who suffer from cardiometabolic and inflammatory diseases.
Pipeline
IndicationInd. | PreclinicalPreclin. | Phase 1/1bPh. 1/1b | Phase 2/2bPh. 2/2b | Phase 3Ph. 3 | PartnerPart. | ||||
---|---|---|---|---|---|---|---|---|---|
Clinical Programs | |||||||||
ECC5004 SM GLP-1RA | ECC5004 SM GLP-1RA | T2D | T2D | ![]() | |||||
Weight Management | Weight Management | ![]() | |||||||
Weight Management / T2D{sup}(2){/sup} | Weight Management / T2D{sup}(2){/sup} | ||||||||
ECC4703 THR-β Agonist | ECC4703 THR-β Agonist | MASH | MASH | ||||||
Weight Management | Weight Management | ||||||||
ECC0509 SSAO Inhibitor | ECC0509 SSAO Inhibitor | OA Pain | OA Pain | ||||||
MASH | MASH | ||||||||
Preclinical Programs | |||||||||
GIP Program SM GIPR | GIP Program SM GIPR | Metabolic Diseases | Metabolic Diseases | ||||||
Amylin Program SM AmylinR | Amylin Program SM AmylinR | Metabolic Diseases | Metabolic Diseases |
(2) China trial
Liver Disease Advisory Board
Contact Us
United States
255 Main Street, Suite 1002
Cambridge, MA 02142
General: info@eccogene.com
Media: Media@eccogene.com
Investors: Investors@eccogene.com
China
Rm. 402A, No. 326, AiDiSheng Road
Zhangjiang, Pudong New District
Shanghai, 201203